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Lumiliximab: Wikis

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Lumiliximab ?
Monoclonal antibody
Type whole antibody
Source chimeric
Target CD23
Identifiers
ATC code none
Chemical data
Formula C2115H3252N556O673S16 
Mol. mass 47.75 kDa
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Lumiliximab is a chimeric monoclonal antibody that targets CD23. It acts as an immunomodulator[1] and, as of October 2009, it is being investigated in Phase I and II clinical trials for the treatment of chronic lymphocytic leukemia.[2][3]

References

  1. ^ International Nonproprietary Names for Pharmaceutical Substances (INN). World Health Organization.
  2. ^ Byrd, J. C.; Kipps, T. J.; Flinn, I. W.; Castro, J.; Lin, T. S.; Wierda, W.; Heerema, N.; Woodworth, J. et al. (2009). "Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia". Blood. doi:10.1182/blood-2009-08-237727.  edit
  3. ^ ClinicalTrials.gov NCT00801060
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