The Full Wiki

More info on Lymphotoxin

Lymphotoxin: Wikis

Advertisements
  

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

lymphotoxin alpha (TNF superfamily, member 1)
Identifiers
Symbol LTA
Alt. symbols TNFB
Entrez 4049
HUGO 6709
OMIM 153440
RefSeq NM_000595
UniProt P01374
Other data
Locus Chr. 6 p21.3
lymphotoxin beta (TNF superfamily, member 3)
Identifiers
Symbol LTB
Alt. symbols TNFC
Entrez 4050
HUGO 6711
OMIM 600978
RefSeq NM_002341
UniProt Q06643
Other data
Locus Chr. 6 p21.3

Lymphotoxin (also known as tumor necrosis factor-beta) is a lymphokine cytokine.

It is a protein that is produced by "killer" CD8+ T cells that kill the virally infected cells by producing holes in the cell's cell membrane.

See also

Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs.

External links

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message