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Systematic (IUPAC) name
CAS number 74698-47-8
ATC code  ?
PubChem 98528
ChemSpider 88979
Chemical data
Formula C10H13NO3
Mol. mass 195.22 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

3,4-Methylenedioxy-N-hydroxyamphetamine (MDOH, MDH) is an entactogen, psychedelic, and stimulant of the phenethylamine and amphetamine chemical classes. It is the N-hydroxy homologue of MDA, and the N-desmethyl homologue of MDHMA. MDOH was first synthesized and assayed by Alexander Shulgin.[1] In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin listed the dosage range as 100-160 mg, and the duration as approximately 3-6 hours.[2] He describes MDOH as being very psychedelic and producing increased pleasure in beauty and nature.[3] He also mentioned several negative side effects also seen with MDMA ("Ecstasy") such as difficulty urinating and internal dryness.[4]

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IUPAC name
CAS number [74698-47-8]
Molecular formula C10H13NO3
Molar mass 195.22 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox references

MDOH, or 3,4-methylenedioxy-N-hydroxyamphetamine, is a lesser-known psychedelic drug and a substituted amphetamine. MDOH was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the dosage range is listed as 100-160mg, and the duration is listed as approximately 3-6 hours. MDOH produces an increased pleasure in beauty and in nature, and is very psychedelic. It also produces several negative effects also seen in MDMA, such as difficulty urinating and internal dryness. Very little data exists about the pharmacological properties, metabolism, and toxicity of MDOH.

See also

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