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2,5-Dimethoxy-4-ethoxyamphetamine
Systematic (IUPAC) name
1-[(4-ethoxy-2,5-dimethoxy)phenyl]propan-2-amine
Identifiers
CAS number 16128-88-4
ATC code  ?
PubChem 542053
ChemSpider 472023
Chemical data
Formula C13H21NO3
Mol. mass 239.31 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

2,5-Dimethoxy-4-ethoxyamphetamine (MEM) is a psychedelic drug of the phenethylamine and amphetamine chemical classes. It was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, he lists the active dose range as 20–50 mg, and the duration as 10–14 hours.[1] According to Shulgin, MEM produces color enhancement, visual phenomena, and pattern movement, among other effects.[1]

MEM possesses affinity (Ki) for the 5-HT2A (3,948 nM), 5-HT2B (64.5 nM), 5-HT7 (7,156 nM), and σ1 (5,077 nM) receptors. It behaves as a partial agonist at the 5-HT2A receptor.[2] MEM is relatively selective for these sites and displays low/negligible (> 10,000 nM) affinity for a wide array of other targets.[2]

See also

References

  1. ^ a b c Ann Shulgin; Alexander Shulgin (1991). Pihkal: A Chemical Love Story. Transform Press. ISBN 0-9630096-0-5. 
  2. ^ a b Ray TS (2010). "Psychedelics and the human receptorome". Plos One 5 (2): e9019. doi:10.1371/journal.pone.0009019. PMID 20126400. 

External links


MEM (psychedelic)
IUPAC name
Identifiers
CAS number [16128-88-4]
SMILES
Properties
Molecular formula C13H21NO3
Molar mass 239.311 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox references

MEM, or 2,5-dimethoxy-4-ethoxyamphetamine, is a lesser-known psychedelic drug. It is a dimethoxy-ethoxy analog of TMA-2. MEM was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the dosage range is listed as 20-50mg, and the duration listed as 10-14 hours. MEM produces insights, and augments the effects of other drugs, like 2C-D. Shulgin gives it a +++ on the Shulgin Rating Scale. Very little data exists about the pharmacological properties, metabolism, and toxicity of MEM.

See also

External links








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