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MPPF
MPPF.png
IUPAC name
Identifiers
CAS number 155204-26-5
PubChem 6603915
SMILES
Properties
Molecular formula C25H27FN4O2
Molar mass 434.51 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

MPPF, with the full name 2'-methoxyphenyl-(N-2'-pyridinyl)-p-fluoro-benzamidoethyipiperazine, is a compound that binds to the serotonin-1A receptor. Labeled with fluorine-18 it has been used as a radioligand with positron emission tomography.[1] It has, e.g., been used to examine the difference in neuroreceptor binding in the human brain across sex and age.[2]

See also

References

  1. ^ D. Le Bars (May 1998). "High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635". Nuclear Medicine and Biology 25 (4): 343–350. doi:10.1016/S0969-8051(97)00229-1.  
  2. ^ Nicolas Costes (December 2005). "A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging". The Journal of Nuclear Medicine 46 (12): 1980–1989. PMID 16330560.  
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