The Full Wiki

More info on MYH13

MYH13: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
myosin, heavy chain 13, skeletal muscle
Identifiers
Symbol MYH13
External IDs OMIM603487 MGI1339967 HomoloGene55780 GeneCards: MYH13 Gene
Orthologs
Species Human Mouse
Entrez 8735 544791
Ensembl ENSG00000006788 ENSMUSG00000060180
UniProt Q9UKX3 B1AR69
RefSeq (mRNA) NM_003802 NM_001081250
RefSeq (protein) NP_003793 NP_001074719
Location (UCSC) Chr 17:
10.13 - 10.22 Mb
Chr 11:
67.14 - 67.19 Mb
PubMed search [1] [2]

Myosin-13 also known as myosin, heavy chain 13 is a protein which in humans is encoded by the MYH13 gene.[1]

Function

MYH13 is a myosin whose expression is restricted primarily to the extrinsic eye muscles which are specialized for function in eye movement.[2]

References

  1. ^ Winters LM, Briggs MM, Schachat F (November 1998). "The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17". Genomics 54 (1): 188–9. doi:10.1006/geno.1998.5558. PMID 9806854. 
  2. ^ Weiss A, Schiaffino S, Leinwand LA (July 1999). "Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity". J. Mol. Biol. 290 (1): 61–75. doi:10.1006/jmbi.1999.2865. PMID 10388558. 

Further reading

  • Weiss A, McDonough D, Wertman B, et al. (1999). "Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.". Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2958-63. PMID 10077619. 
  • Schachat F, Briggs MM (2002). "Phylogenetic implications of the superfast myosin in extraocular muscles.". J. Exp. Biol. 205 (Pt 15): 2189-201. PMID 12110653. 
  • Trynka G, Zhernakova A, Romanos J, et al. (2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.". Gut 58 (8): 1078-83. doi:10.1136/gut.2008.169052. PMID 19240061. 
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315-23. doi:10.1101/gr.2122004. PMID 15231747. 
  • Schjeide BM, McQueen MB, Mullin K, et al. (2009). "Assessment of Alzheimer's disease case-control associations using family-based methods.". Neurogenetics 10 (1): 19-25. doi:10.1007/s10048-008-0151-3. PMID 18830724. 
  • Shoeman RL, Sachse C, Höner B, et al. (1993). "Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.". Am. J. Pathol. 142 (1): 221-30. PMID 8424456. 
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message