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myosin, heavy chain 15
Identifiers
Symbol MYH15
External IDs OMIM609929 MGI3643515 HomoloGene18929 GeneCards: MYH15 Gene
Orthologs
Species Human Mouse
Entrez 22989 667772
Ensembl ENSG00000144821 n/a
UniProt Q9Y2K3 n/a
RefSeq (mRNA) NM_014981 XM_992311
RefSeq (protein) NP_055796 XP_997405
Location (UCSC) Chr 3:
109.58 - 109.73 Mb
Chr 16:
49.06 - 49.2 Mb
PubMed search [1] [2]

Myosin-15 also known as myosin, heavy chain 15 is a protein that in humans is encoded by the MYH15 gene.[1]

Function

MYH15 is a slow-twitch myosin.[1]

References

  1. ^ a b Desjardins PR, Burkman JM, Shrager JB, Allmond LA, Stedman HH (April 2002). "Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family". Mol. Biol. Evol. 19 (4): 375–93. PMID 11919279. 

Further reading

  • Luke MM, O'Meara ES, Rowland CM, et al. (2009). "Gene variants associated with ischemic stroke: the cardiovascular health study.". Stroke 40 (2): 363-8. doi:10.1161/STROKEAHA.108.521328. PMID 19023099. 
  • Rossi AC, Mammucari C, Argentini C, et al. (2010). "Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.". J. Physiol. (Lond.) 588 (Pt 2): 353-64. doi:10.1113/jphysiol.2009.181008. PMID 19948655. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Stedman HH, Kozyak BW, Nelson A, et al. (2004). "Myosin gene mutation correlates with anatomical changes in the human lineage.". Nature 428 (6981): 415-8. doi:10.1038/nature02358. PMID 15042088. 
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63-70. PMID 10231032. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • McGuigan K, Phillips PC, Postlethwait JH (2004). "Evolution of sarcomeric myosin heavy chain genes: evidence from fish.". Mol. Biol. Evol. 21 (6): 1042-56. doi:10.1093/molbev/msh103. PMID 15014174. 
  • Shiffman D, O'Meara ES, Bare LA, et al. (2008). "Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.". Arterioscler. Thromb. Vasc. Biol. 28 (1): 173-9. doi:10.1161/ATVBAHA.107.153981. PMID 17975119. 
  • Bare LA, Morrison AC, Rowland CM, et al. (2007). "Five common gene variants identify elevated genetic risk for coronary heart disease.". Genet. Med. 9 (10): 682-9. doi:10.1097/GIM.0b013e318156fb62. PMID 18073581. 
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