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Masoprocol
Systematic (IUPAC) name
4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
Identifiers
CAS number 500-38-9
ATC code L01XX10
PubChem 71398
DrugBank APRD01084
Chemical data
Formula C 18H22O4  
Mol. mass 302.365 g/mol
Pharmacokinetic data
Bioavailability Very low
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. B(US)
Legal status
Routes Topical

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Also called nordihydroguaiaretic acid, NDGA, and actinex.

Mechanism

Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.

It is a lipoxygenase inhibitor.[1]

References

External links

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