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Mebhydrolin
Systematic (IUPAC) name
5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3- b]indole
Identifiers
CAS number 524-81-2 6153-33-9[1]
ATC code R06AX15
PubChem 22530
Chemical data
Formula C 19H20N2[2]  
Mol. mass 276.376 g/mol
SMILES eMolecules & PubChem
Synonyms 9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-β-carboline, Incidal, Omeril, diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. Not established[4]
Legal status
Routes oral[4]

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries. It is also called Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.[5]

References

  1. ^ "Diazoline" (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=diazoline. Retrieved 2007-03-02.  
  2. ^ "Mebhydrolin chemical information" (HTML). PubChem. http://www.chemindustry.com/chemicals/969111.html. Retrieved 2007-03-02.  
  3. ^ "Mebhydroline" (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=mebhydroline. Retrieved 2007-03-02.  
  4. ^ a b "FABAHISTIN 50 mg (Tablets)" (HTML). South African Electronic Package Inserts. 1970-09. http://www.intekom.com/pharm/bayer/fabahist.html. Retrieved 2007-03-02.  
  5. ^ Franks, HM; M. Lawrie, VV Schabinsky, GA Starmer, RK Teo (1981-10-31). "Interaction between ethanol and antihistamines: 3. mebhydrolin." (in English) (HTML). Med J Aust.. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6119605&dopt=Abstract. Retrieved 2007-03-02.  
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