The Full Wiki

More info on Mecloqualone

Mecloqualone: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
3-(2-chlorophenyl)-2-methylquinazolin-4(3 H)-one
CAS number 340-57-8
ATC code none
PubChem 9567
Chemical data
Formula C 15H11ClN2O 
Mol. mass 270.714
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Mecloqualone (Nubarene, Casfen) is an analogue of methaqualone which was first made in 1960[1] and marketed mainly in France and some other European countries. It has sedative, hypnotic and anxiolytic properties, and was used for the treatment of insomnia.[2] Mecloqualone is faster acting but shorter lasting than methaqualone and so was used only as a sleeping pill[3], in contrast to methaqualone which was used as a general purpose anxiolytic as well. Mecloqualone was never as widely used as methaqualone and is no longer prescribed because of concerns about its potential for abuse and overdose.

See also


  1. ^ Jackman GV, Petrow V, Stephenson O. Journal of Pharmacy and Pharmacology 1960; 12(9):528-9.
  2. ^ Mouren P, Giraud F, Pinsard N. "Clinical use of a new psycholeptic: Mecloqualone." (French) Marseille Medical 1963;100: 599-602. PMID 13936358
  3. ^ Dubnk B, Towne CA, Bush MT. "Detection, assay and rate of excretion of mecloqualone in animals and man." Toxicology and Applied Pharmacology 1969 Nov;15(3):632-41. PMID 5353825


Got something to say? Make a comment.
Your name
Your email address