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Mesenchyme: Wikis


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Mesenchyme with a typical cell and ground substance
Mesenchyme (pointer) stained with H&E

Mesenchyme, or mesenchymal connective tissue, is an example of reticular connective tissue, a type of loose connective tissue, which is derived from all three germ layers and located within the embryo .[1] Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibrils and unspecialized cells.[2] The cells are capable of developing into connective tissue, bone, cartilage, the lymphatic system, and the circulatory system.[3][4]



Ectomesenchyme has similar properties to mesenchyme. The major difference is that ectomesenchyme is usually considered to arise from neural crest cells,[5] which are a critical group of cells that form in the cranial region during early vertebrate development. Thus, ectomesenchyme plays a critical role in the formation of the hard and soft tissues of the head and neck such as bones, muscles and most importantly the branchial arches.

See also


  1. ^ Loose connective tissue
  2. ^ Mesenchymal tissue
  3. ^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstwon, MD: Lippincott Williams & Wilkins. pp. 83. ISBN 0-7817-8577-4.  
  4. ^ Sadler, T.W. (2006). Langman's Medical Embryology. Lippincott Williams & Wilkins. pp. 68–70. ISBN 0-7817-9485-4.  
  5. ^ Weston JA, Yoshida H, Robinson V, Nishikawa S, Fraser ST, Nishikawa S (2004). "Neural crest and the origin of ectomesenchyme: neural fold heterogeneity suggests an alternative hypothesis". Dev. Dyn. 229 (1): 118–30. doi:10.1002/dvdy.10478. PMID 14699583.  


External links

Latin mesenchyma
Carnegie stage 6b
Precursor primarily mesoderm

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