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Mesial Temporal Sclerosis
Classification and external resources
DiseasesDB 34097

Mesial temporal sclerosis is a specific pattern of hippocampal neuron cell loss[1] [2]. There are 3 specific patterns of cell loss; Cell loss might involve sectors CA1 and CA4, CA4 alone, or CA1 to CA4 [3]. Associated hippocampal atrophy and gliosis is common[4]. MRI scan commonly displays increased T2 signal and hippocampal atrophy [5] Mesial temporal sclerosis might occur with other temporal lobe abnormalities (dual pathology) [6]. Mesial temporal sclerosis is the most common pathological abnormality in temporal lobe epilepsy[7] [8].

Contents

See also

Notes

  1. ^ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
  2. ^ Trepeta, Scott 2007
  3. ^ Trepeta, Scott 2007
  4. ^ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
  5. ^ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
  6. ^ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
  7. ^ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
  8. ^ Trepeta, Scott 2007

References

  • Bronen RA, Fulbright RK, Spencer DD, et al. Refractory epilepsy: comparison of MR imaging, CT, and histopathologic findings in 117 patients. Radiology. Oct 1996;201(1):97-105
  • Trepeta, Scott. "eMedicine - Mesial Temporal Sclerosis." 11 Sept. 2007. Jamaica Hospital. 9 Apr. 2008 <http://www.emedicine.com/radio/topic443.htm>

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