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Mesuximide: Wikis

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Mesuximide
Systematic (IUPAC) name
(RS)-1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione
Identifiers
CAS number 77-41-8
ATC code N03AD03
PubChem 6476
Chemical data
Formula C 12H13NO2  
Mol. mass 203.237 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic (demethylation and glucuronidation)
Half life 1.4–2.6 hours (mesuximide)
28–38 hours (active metabolite)
Excretion Renal
Therapeutic considerations
Pregnancy cat. C(US)
Legal status -only (US)
Routes Oral

Mesuximide (or methsuximide) is an succinimide anticonvulsant medication. It is sold by Pfizer under the tradenames Petinutin (Switzerland)[1] and Celontin (United States).[2]

References

  1. ^ Pfizer AG (2005). "Petinutin (Mésuximide)" (in French). Official Pfizer AG Website. http://www.pfizer.ch/internet/fr/home/products/central_nervous_system/epilepsy/petinutin_mesuximid.html. Retrieved August 21 2006.  
  2. ^ Pfizer Inc. (2008). "Celontin (methsuximide capsules, USP)". Official Pfizer Inc. Website. http://www.pfizer.com/products/rx/rx_product_celontin.jsp. Retrieved June 10 2008.  
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