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Metaraminol: Wikis


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Systematic (IUPAC) name
CAS number 54-49-9
ATC code C01CA09
PubChem 5906
DrugBank APRD00555
Chemical data
Formula C 9H13NO2  
Mol. mass 167.205 g/mol
Pharmacokinetic data
Bioavailability n/a
Protein binding ~45%
Metabolism Hepatic
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. C(AU) C(US)
Legal status POM (UK)
Routes Intravenous

Metaraminol (INN, trade name Aramine) is a potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. It is an α1-adrenergic receptor agonist with some β effect.

Metaraminol is also used in the treatment of priapism. Although not approved for this use, it appears to be effective.[1][2][3]

See also


  1. ^ McDonald M, Santucci R (2004). "Successful management of stuttering priapism using home self-injections of the alpha-agonist metaraminol.". Int Braz J Urol 30 (2): 121–2. doi:10.1590/S1677-55382004000200007. PMID 15703094.  
  2. ^ Koga S, Shiraishi K, Saito Y (1990). "Post-traumatic priapism treated with metaraminol bitartrate: case report.". J Trauma 30 (12): 1591–3. doi:10.1097/00005373-199012000-00029. PMID 2258979.  
  3. ^ Block T, Sturm W, Ernst G, Staehler G, Schmiedt E (1988). "[Metaraminol in therapy of various forms of priapism]". Urologe A 27 (4): 225–9. PMID 3140463.  


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