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Methoxymethylenedioxyphenethylamine: Wikis


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Systematic (IUPAC) name
CAS number  ?
ATC code  ?
PubChem  ?
Chemical data
Formula C 10H13NO3  
Mol. mass 195.22 g/mol
Synonyms 3-methoxy-1,3-benzodioxolyl-5-ethanamine;
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
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Therapeutic considerations
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Various

3-Methoxy-4,5-methylenedioxyphenethylamine (MMDPEA), also known as lophophine and homomyristicylamine, is a psychoactive drug and research chemical of the phenethylamine chemical class which acts as an entactogen, psychedelic, and stimulant, as well as an entheogen. It is the α-demethylated or phenethylamine homologue of 3-methoxy-4,5-methylenedioxyamphetamine (MMDA).

MMDPEA is also closely related on a structural level to mescaline. Notably, Alexander Shulgin ("Sasha" Shulgin) previously suggested that it may be a natural constituent of Lophophora williamsii ("Peyote"), due to it being the only logical chemical intermediate for the biosynthesis of several tetrahydroisoquinolines known to be present in the species. Subsequently, it was indeed shown to be a minor component of both Lophophora williamsii and Echinopsis pachanoi ("San Pedro").[1]

Shulgin reports that MMDPEA is active in the dosage range of 150-250 mg. He reports that at these doses, MMDPEA is very similar to mescaline in action, and that a peaceful elevation of mood, euphoria, enhancement of visual perception, and the generation of closed-eye mental imagery are all present. At dosages above 300 mg, visual distortions that resemble those of standard doses of mescaline are said to begin to appear. Shulgin also notes that in contrast to mescaline, MMDPEA causes little nausea or vomiting.

Little else is known regarding the pharmacology, pharmacokinetics, effects, and toxicity of MMDPEA.

See also


  1. ^ Bruhn JG, El-Seedi HR, Stephanson N, Beck O, Shulgin AT (June 2008). "Ecstasy analogues found in cacti". Journal of Psychoactive Drugs 40 (2): 219–22. PMID 18720674.  

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