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Metitepine
Systematic (IUPAC) name
1-methyl-4-(8-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)piperazine
Identifiers
CAS number 20229-30-5
ATC code  ?
PubChem 4106
ChemSpider 3963
Chemical data
Formula C20H24N2S2
Mol. mass 356.55 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Metitepine (INN), also commonly known as methiothepin, is a drug that acts as an antagonist at various serotonin and dopamine receptors.[1][2] It is used as an antipsychotic.

References

  1. ^ Monachon MA, Burkard WP, Jalfre M, Haefely W (1972). "Blockade of central 5-hydroxytryptamine receptors by methiothepin". Naunyn Schmiedebergs Arch. Pharmacol. 274 (2): 192–7. doi:10.1007/BF00501854. PMID 4340797.  
  2. ^ Dall'Olio R, Vaccheri A, Montanaro N (1985). "Reduced head-twitch response to quipazine of rats previously treated with methiothepin: possible involvement of dopaminergic system". Pharmacol. Biochem. Behav. 23 (1): 43–8. doi:10.1016/0091-3057(85)90128-5. PMID 2994121.  

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