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Mibefradil: Wikis


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Systematic (IUPAC) name
(1S,2S)-2-(2-((3-(1H-benzo[ d]imidazol-2-yl)propyl) (methyl)amino)ethyl)-6-fluoro-1-isopropyl- 1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
CAS number 116644-53-2
ATC code C08CX01
PubChem 60662
Chemical data
Formula C 29H38FN3O3  
Mol. mass 495.63 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Withdrawn from market
Routes Oral

Mibefradil (Posicor) is a drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers.

It is nonselective.[1]

On June 8, 1998, Roche announced the voluntary withdrawal of the drug from the market,[2] due to the potential for drug interactions, some of them serious, which may occur when it is taken together with some other medications.




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