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Minaprine
Systematic (IUPAC) name
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Identifiers
CAS number 25905-77-5
ATC code N06AX07
PubChem 4199
Chemical data
Formula C17H22N4O 
Mol. mass 298.383 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Half life 2-2.5 hours
Therapeutic considerations
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral
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Minaprine (Brantur, Cantor) is an antidepressant used in France for the treatment of depression. It acts as a reversible inhibitor of MAO-A (RIMA).[1] It has also been found to inhibit acetylcholinesterase.[2]

See also

References

  1. ^ Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochemical Pharmacology. 1986 Mar 15;35(6):973-8. PMID 3954800
  2. ^ Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. Journal of Medicinal Chemistry. 1999 Feb 25;42(4):730-41. PMID 10052979







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