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Monobactams: Wikis


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Aztreonam. (The square is the beta-lactam. There is a second thiazole ring, but it is not fused to the beta-lactam ring)

Monobactams are beta-lactam compounds wherein the beta-lactam ring is alone and not fused to another ring (in contrast to most other beta-lactams, which have at least two rings). They work only against Gram-negative bacteria.[citation needed]

The only commercially available monobactam antibiotic is aztreonam.

Other examples of monobactams are tigemonam,[1] nocardicin A, and tabtoxin.


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Only aerobic GNR!!!



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