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MSLT Scores
Minutes Sleepiness
0-5 Severe
5-10 Troublesome
10-15 Manageable
15-20 Excellent

The Multiple Sleep Latency Test (MSLT) is a sleep disorder diagnostic tool. It is used to measure the time it takes from the start of a daytime nap period to the first signs of sleep, called sleep latency. The test is based on the idea that the sleepier people are, the faster they will fall asleep.

It can be used to test for narcolepsy, to distinguish between physical tiredness and true excessive daytime sleepiness, or to see if breathing disorder treatments are working. Its main purpose is to serve as an objective measure of sleepiness.

The test consists of four or five, twenty minute nap opportunities that are scheduled about two hours apart. The test is often done following an overnight sleep study. During the test, things such as the patient's brain waves, EEG, muscle activity and eye movements are monitored and recorded. The entire test normally takes about 7 hours.

The MSLT may also be used extensively to test sleepiness in a number of research protocols.

Contents

History

The Multiple Sleep Latency Test was created in 1977 by sleep pioneers William C. Dement and Mary Carskadon.[1][2][3][4] It developed out of repeating a project done in 1970 by Dr. Dement called the 90-minute day.[5] They informally called the 0-5 minute range the twilight zone due to its indication of extreme physical and mental impairment.

Typical procedure

Preparation: On the day of the test the patient is asked to not take any stimulants such as tea, coffee, colas and chocolate.

  • Often a formal sleep study has been done the night before.
  • Sometimes urine screening is done to make sure no substances exist in the subject's body that might interfere with sleep.
  • The patient may be asked to fill out a pre-test questionnaire.
  • Electrodes are attached to the patient's head to record brain waves.
  • Electrodes are attached by the eyes to record eye movement.
  • Electrodes are attached to the chin to detect muscle tone.
  • Heart beat may also be monitored.
  • Patients are asked to perform simple tasks to test that the equipment is working properly.
  • The patient is asked to nap for 20 minutes after which they are awoken.
  • The nap process is repeated every two hours, 4 or 5 times.
  • The patient may be asked to fill out a post-test questionnaire.

A clinical neurophysiologist, neurologist or sleep specialist will review the results and inform the patient or the patient's primary care physician of the interpretation of the test result in the context of the clinical problem.

References

  1. ^ Carskadon, M.A. and Dement, W.C. Sleep tendency: an objective measure of sleep loss. Sleep Research 6: 200, 1977.
  2. ^ Richardson GS, Carskadon MA, Flagg W, Van den Hoed J, Dement WC, Mitler MM. Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. Electroencephalogr Clin Neurophysiol. 1978 Nov;45(5):621–627.
  3. ^ Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S: Guidelines for the Multiple Sleep Latency Test (MSLT): a standard measure of sleepiness. Sleep 1986; 9:519–524
  4. ^ Thorpy MJ, Westbrook P, Ferber R, Fredrickson P, Mahowald M, Perez-Guerra F, Reite M, Smith P: The clinical use of the Multiple Sleep Latency Test. Sleep 1992; 15:268–276.
  5. ^ Carskadon, M.A. and Dement, W.C. Sleep studies on a 90-minute day. Electroencephalogr. Clin. Neurophysiol. 39: 145-155, 1975.

External links

Mary Carskadon's page on the MSLT [1]

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