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N-Methyltryptamine: Wikis

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Systematic (IUPAC) name
CAS number 61-49-4
ATC code  ?
PubChem 6088
Chemical data
Formula C 11H14N2  
Mol. mass 174.245 g/mol
SMILES eMolecules & PubChem
Physical data
Melt. point 87–89 °C (189–192 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

N-Methyltryptamine (NMT), or merely methyltryptamine, is a putative psychoactive drug of the tryptamine chemical class which may purportedly have psychedelic properties. It is an alkaloid that has been found in the bark, shoots and leaves of several species of Virola, Acacia and Mimosa plants, among others, many of which also contain the related compounds N,N-dimethyltryptamine (DMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). It is also synthetized in the body by humans as a metabolic endproduct of the amino acid L-tryptophan (see External links for more information).

Upon ingestion, NMT appears to produce no psychoactive effects on its own whatsoever, likely as a result of extensive first-pass metabolism. However, it may very well become active upon combination with a MAOA inhibitor (MAOI), identical in concept to the strategy of using the harmala alkaloids or other MAOIs to bring the normally inactive orally-consumed ayahausca (which contains DMT, 5-MeO-DMT, etc) preparations into prominent psychoactivity.

See also


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