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NBUMP
Systematic (IUPAC) name
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]adamantane-1-carboxamide
Identifiers
ATC code none
PubChem 64622
Chemical data
Formula C26H39N3O2 
Mol. mass 425.607 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status

NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure.[1] It is one of the highest affinity ligands for the 5-HT1A receptor known.[1] It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.[1]

See also

References

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