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NEFA (drug): Wikis

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NEFA (drug)
Systematic (IUPAC) name
(4aR,9aS)-N-Ethyl-4,4a,9,9a-tetrahydro-1 H-fluoren-4a-amine
CAS number  ?
ATC code  ?
PubChem  ?
Chemical data
Formula C 15H19N 
Mol. mass 213.3181 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

NEFA is a moderate affinity NMDA antagonist (IC50 = 0.51 μM). It is a structural analog of phencyclidine.[1]


  1. ^ Dilmore JG, Johnson JW (1998). "Open channel block and alteration of N-methyl-D-aspartic acid receptor gating by an analog of phencyclidine". Biophysical Journal 75 (4): 1801–16.  

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