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NFIC (gene): Wikis


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Nuclear factor I/C (CCAAT-binding transcription factor)
Symbols NFIC; CTF; CTF5; MGC20153; NF-I; NFI
External IDs OMIM600729 MGI109591 HomoloGene4088 GeneCards: NFIC Gene
RNA expression pattern
PBB GE NFIC 206929 s at tn.png
PBB GE NFIC 213298 at tn.png
More reference expression data
Species Human Mouse
Entrez 4782 18029
Ensembl ENSG00000141905 ENSMUSG00000055053
UniProt P08651 Q3UHA6
RefSeq (mRNA) NM_005597 NM_008688
RefSeq (protein) NP_005588 NP_032714
Location (UCSC) Chr 19:
3.31 - 3.41 Mb
Chr 10:
80.8 - 80.83 Mb
PubMed search [1] [2]

Nuclear factor 1 C-type is a protein that in humans is encoded by the NFIC gene.[1][2][3]


  1. ^ Santoro C, Mermod N, Andrews PC, Tjian R (Aug 1988). "A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs". Nature 334 (6179): 218-24. doi:10.1038/334218a0. PMID 3398920.  
  2. ^ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics 28 (1): 66-73. doi:10.1006/geno.1995.1107. PMID 7590749.  
  3. ^ "Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)".  

Further reading

  • Blau J, Xiao H, McCracken S, et al. (1996). "Three functional classes of transcriptional activation domain.". Mol. Cell. Biol. 16 (5): 2044–55. PMID 8628270.  
  • Wenzelides S, Altmann H, Wendler W, Winnacker EL (1996). "CTF5--a new transcriptional activator of the NFI/CTF family.". Nucleic Acids Res. 24 (12): 2416–21. doi:10.1093/nar/24.12.2416. PMID 8710515.  
  • Liu Y, Bernard HU, Apt D (1997). "NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.". J. Biol. Chem. 272 (16): 10739–45. doi:10.1074/jbc.272.16.10739. PMID 9099724.  
  • Nogues G, Kadener S, Cramer P, et al. (2003). "Transcriptional activators differ in their abilities to control alternative splicing.". J. Biol. Chem. 277 (45): 43110–4. doi:10.1074/jbc.M208418200. PMID 12221105.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Norquay LD, Yang X, Sheppard P, et al. (2003). "RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin.". Mol. Endocrinol. 17 (6): 1027–38. doi:10.1210/me.2003-0025. PMID 12624117.  
  • Wickenheisser JK, Nelson-DeGrave VL, Quinn PG, McAllister JM (2004). "Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1.". Mol. Endocrinol. 18 (3): 588–605. doi:10.1210/me.2003-0090. PMID 14684846.  
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.  
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Zhao LH, Ba XQ, Wang XG, et al. (2005). "BAF complex is closely related to and interacts with NF1/CTF and RNA polymerase II in gene transcriptional activation.". Acta Biochim. Biophys. Sin. (Shanghai) 37 (7): 440–6. doi:10.1111/j.1745-7270.2005.00061.x. PMID 15999204.  
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  
  • Nilsson J, Bjursell G, Kannius-Janson M (2006). "Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cells.". Mol. Cell. Biol. 26 (15): 5663–74. doi:10.1128/MCB.02095-05. PMID 16847321.  
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.  
  • Hebbar PB, Archer TK (2007). "Chromatin-dependent cooperativity between site-specific transcription factors in vivo.". J. Biol. Chem. 282 (11): 8284–91. doi:10.1074/jbc.M610554200. PMID 17186943.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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