The Full Wiki

NPR1: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
Identifiers
Symbols NPR1; ANPRA; ANPa; GUC2A; GUCY2A; NPRA
External IDs OMIM108960 MGI97371 HomoloGene37367 GeneCards: NPR1 Gene
RNA expression pattern
PBB GE NPR1 32625 at tn.png
PBB GE NPR1 204648 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4881 18160
Ensembl ENSG00000169418 ENSMUSG00000027931
UniProt P16066 Q2TAY4
RefSeq (mRNA) NM_000906 NM_008727
RefSeq (protein) NP_000897 NP_032753
Location (UCSC) Chr 1:
151.92 - 151.93 Mb
Chr 3:
90.54 - 90.55 Mb
PubMed search [1] [2]

Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is a protein that in humans is encoded by the NPR1 gene.

Contents

Function

NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP and BNP, respectively).[1]

References

Further reading

  • Pandey KN (2002). "Intracellular trafficking and metabolic turnover of ligand-bound guanylyl cyclase/atrial natriuretic peptide receptor-A into subcellular compartments.". Mol. Cell. Biochem. 230 (1-2): 61–72. doi:10.1023/A:1014240006767. PMID 11952097.  
  • Lucarelli K, Iacoviello M, Dessì-Fulgheri P, et al. (2003). "[Natriuretic peptides and essential arterial hypertension]". Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 3 (11): 1085–91. PMID 12506509.  
  • Pandey KN (2005). "Internalization and trafficking of guanylyl cyclase/natriuretic peptide receptor-A.". Peptides 26 (6): 985–1000. doi:10.1016/j.peptides.2004.12.020. PMID 15911067.  
  • Garg R, Pandey KN (2005). "Regulation of guanylyl cyclase/natriuretic peptide receptor-A gene expression.". Peptides 26 (6): 1009–23. doi:10.1016/j.peptides.2004.09.022. PMID 15911069.  

See also

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message