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Nalorphine: Wikis


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Systematic (IUPAC) name
(5α,6α)-17-allyl- 7,8-didehydro- 4,5-epoxymorphinan- 3,6-diol
CAS number 62-67-9
ATC code V03AB02
PubChem 5284595
Chemical data
Formula C 19H21NO3  
Mol. mass 311.375 g/mol
Synonyms (−)−(5R,6S)-9α-allyl- 4,5-epoxymorphin- 7-en- 3,6-diol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
 Yes check.svgY(what is this?)  (verify)

Nalorphine (INN, also known as N-allyl-normorphine) trade names Lethidrone and Nalline. Nalorphine acts at two opioid receptors, at the mu receptor it has antagonistic effects and at the kappa receptors it exerts agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.[1]


  1. ^ [,9171,808859,00.html "Medicine: Drug Detector"], Time, Dec. 24, 1956


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