The Full Wiki

More info on Naptumomab estafenatox

Naptumomab estafenatox: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Naptumomab estafenatox ?
Monoclonal antibody
Source Mouse
Target 5T4 Fab
CAS number 676258-98-3
ATC code none
PubChem  ?
Chemical data
Formula C 3255H5025N855O1050S18  
Mol. mass 73.5 kDa
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Naptumomab estafenatox (ABR-217620) is a monoclonal antibody being developed for the treatment of various types of cancer like non-small cell lung carcinoma[1] and renal cell carcinoma[2].


  1. ^ Borghaei, H; Alpaugh, K; Hedlund, G; Forsberg, G; Langer, C; Rogatko, A; Hawkins, R; Dueland, S et al. (2009). "Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer". Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27 (25): 4116–23. doi:10.1200/JCO.2008.20.2515. PMID 19636016.  
  2. ^


Got something to say? Make a comment.
Your name
Your email address