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More info on Naptumomab estafenatox

Naptumomab estafenatox: Wikis

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Naptumomab estafenatox ?
Monoclonal antibody
Source Mouse
Target 5T4 Fab
Identifiers
CAS number 676258-98-3
ATC code none
PubChem  ?
Chemical data
Formula C 3255H5025N855O1050S18  
Mol. mass 73.5 kDa
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Naptumomab estafenatox (ABR-217620) is a monoclonal antibody being developed for the treatment of various types of cancer like non-small cell lung carcinoma[1] and renal cell carcinoma[2].

References

  1. ^ Borghaei, H; Alpaugh, K; Hedlund, G; Forsberg, G; Langer, C; Rogatko, A; Hawkins, R; Dueland, S et al. (2009). "Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer". Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27 (25): 4116–23. doi:10.1200/JCO.2008.20.2515. PMID 19636016.  
  2. ^ ClinicalTrials.gov
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