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Necrobiosis lipoidica
Classification and external resources
File:Necrobiosis Lipoidica, solitary plaque 5.5 x 3.5 cm. right pretibial area.JPG
Necrobiosis Lipoidica
ICD-10 L92.1
ICD-9 709.3
DiseasesDB 5414
eMedicine derm/283
MeSH D009335

Necrobiosis lipoidica is a necrotizing skin condition that usually occurs in patients with diabetes but can also be associated with Rheumatoid Arthritis.[1]:539 In such cases it may be called necrobiosis lipoidica diabeticorum (NLD). NLD occurs in approximately 3% of the diabetic population, with the majority of sufferers being women (approximately 90%).

Necrobiosis lipoidica is closely related to granuloma annulare.


Clinical appearance

NL/NLD most frequently appears on the patient's shins, often on both legs. The lesions are often tender and may become yellowish in the centre and ulcerate when injured. The first symptom of NL/NLD is often a "bruised" appearance (erythematous) that is not necessarily associated with a known injury. The extent to which NL/NLD is inherited is not known.

See also


  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.  

External links



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