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Neuromedin N[1]
Neuromedin N.svg
Identifiers
CAS number 102577-25-3
PubChem 3025353
Properties
Molecular formula C38H63N7O8
Molar mass 745.949
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references
Neuromedin N
Identifiers
Symbol NN
Entrez 4922
HUGO 8038
Other data
Locus Chr. 12 q21

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.[2][3][4][5][6][7]

References

  1. ^ Neuromedin N - Compound Summary, PubChem.
  2. ^ Carraway RE, Mitra SP, Spaulding G (1992). "Posttranslational processing of the neurotensin/neuromedin-N precursor". Annals of the New York Academy of Sciences 668: 1–16. PMID 1463268.  
  3. ^ Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). "Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N". Annals of the New York Academy of Sciences 668: 30–42. PMID 1463273.  
  4. ^ Vincent JP (October 1995). "Neurotensin receptors: binding properties, transduction pathways, and structure". Cellular and Molecular Neurobiology 15 (5): 501–12. PMID 8719037.  
  5. ^ Adams DH, Hanson GR, Keefe KA (2001). "Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum". Neuroscience 102 (4): 843–51. PMID 11182247.  
  6. ^ Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (February 2002). "Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity". Biochemical and Biophysical Research Communications 290 (4): 1161–8. doi:10.1006/bbrc.2001.6308. PMID 11811984.  
  7. ^ Kitabgi P (October 2006). "Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases". Peptides 27 (10): 2508–14. doi:10.1016/j.peptides.2006.03.038. PMID 16904237.  
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