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Neuropeptides B/W receptor 1: Wikis


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Neuropeptides B/W receptor 1
Symbols NPBWR1; GPR7; MGC129755
External IDs OMIM600730 MGI891989 HomoloGene21096 IUPHAR: NPBW1 GeneCards: NPBWR1 Gene
Species Human Mouse
Entrez 2831 226304
Ensembl ENSG00000183729 ENSMUSG00000033774
UniProt P48145 P49681
RefSeq (mRNA) NM_005285 XM_136404
RefSeq (protein) NP_005276 XP_136404
Location (UCSC) Chr 8:
54.01 - 54.02 Mb
Chr 1:
5.91 - 5.91 Mb
PubMed search [1] [2]

Neuropeptides B/W receptor 1, also known as NPBW1, is a human protein encoded by the NPBWR1 gene.[1]


External links

Further reading

  • O'Dowd BF, Scheideler MA, Nguyen T, et al. (1995). "The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.". Genomics 28 (1): 84–91. doi:10.1006/geno.1995.1109. PMID 7590751.  
  • Fujii R, Yoshida H, Fukusumi S, et al. (2002). "Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7.". J. Biol. Chem. 277 (37): 34010–6. doi:10.1074/jbc.M205883200. PMID 12118011.  
  • Shimomura Y, Harada M, Goto M, et al. (2002). "Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.". J. Biol. Chem. 277 (39): 35826–32. doi:10.1074/jbc.M205337200. PMID 12130646.  
  • Brezillon S, Lannoy V, Franssen JD, et al. (2003). "Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.". J. Biol. Chem. 278 (2): 776–83. doi:10.1074/jbc.M206396200. PMID 12401809.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Tanaka H, Yoshida T, Miyamoto N, et al. (2003). "Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8.". Proc. Natl. Acad. Sci. U.S.A. 100 (10): 6251–6. doi:10.1073/pnas.0837789100. PMID 12719537.  
  • Zaratin PF, Quattrini A, Previtali SC, et al. (2005). "Schwann cell overexpression of the GPR7 receptor in inflammatory and painful neuropathies.". Mol. Cell. Neurosci. 28 (1): 55–63. doi:10.1016/j.mcn.2004.08.010. PMID 15607941.  
  • Mazzocchi G, Rebuffat P, Ziolkowska A, et al. (2005). "G protein receptors 7 and 8 are expressed in human adrenocortical cells, and their endogenous ligands neuropeptides B and w enhance cortisol secretion by activating adenylate cyclase- and phospholipase C-dependent signaling cascades.". J. Clin. Endocrinol. Metab. 90 (6): 3466–71. doi:10.1210/jc.2004-2132. PMID 15797961.  
  • Cottrell S, Jung K, Kristiansen G, et al. (2007). "Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis.". J. Urol. 177 (5): 1753–8. doi:10.1016/j.juro.2007.01.010. PMID 17437806.  


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