The Full Wiki

More info on Nicodicodeine

Nicodicodeine: Wikis

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
(5α,6α)-3-methoxy- 17-methyl- 4,5-epoxymorphinan- 6-yl nicotinate
CAS number 808-24-2
ATC code none
PubChem 5464304
Chemical data
Formula C24H26N2O4 
Mol. mass 406.474 g/mol
Synonyms 6-Nicotinoyldihydrocodeine
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule I (US)
Routes Oral, intravenous

Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. Synthesized in 1904, it is not commonly used, but has activity similar to other opiates. Nicodicodeine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodeine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression.

Got something to say? Make a comment.
Your name
Your email address