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Nifurtoinol
Systematic (IUPAC) name
3-(hydroxymethyl)-1-{[(1E)-(5-nitro-2-furyl)
methylene]amino}imidazolidine-2,4-dione
Identifiers
CAS number 1088-92-2
ATC code J01XE02
PubChem 9571062
Chemical data
Formula C 9H8N4O6  
Mol. mass 268.183 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion Renal (40–50% within the first 12 hours)
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral

Nifurtoinol (rINN, trade name Urfadyn) is a nitrofuran-derivative antibiotic used in the treatment of urinary tract infections.

It is also known as "hydroxymethylnitrofurantoin".[1]

References

  1. ^ Stricker BH, Blok AP, Claas FH, Van Parys GE, Desmet VJ (1988). "Hepatic injury associated with the use of nitrofurans: a clinicopathological study of 52 reported cases". Hepatology 8 (3): 599–606. PMID 3371877.  
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