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Nilutamide: Wikis


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Systematic (IUPAC) name
CAS number 63612-50-0
ATC code L02BB02
PubChem 4493
DrugBank APRD00150
Chemical data
Formula C 12H10F3N3O4  
Mol. mass 317.221 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 38.0 to 59.1 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status pr
Routes oral

Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer. Nilutamide blocks the androgen receptor, preventing its interaction with testosterone. Because most prostate cancer cells rely on the stimulation of the androgen receptor for growth and survival, nilutamide can prolong life in men with prostate cancer. Nilutamide is marketed under the name Nilandron in the United States and under the name Anandron in Canada.


  • Kassouf W, Tanguay S, Aprikian AG. Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails. J. Urol. 2003 May;169(5):1742-4. PMID 12686822


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