The Full Wiki

More info on Niobocene dichloride

Niobocene dichloride: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Niobocene dichloride
IUPAC name
Other names Niobocene dichloride
CAS number 12793-14-5
RTECS number QU0400000
Molecular formula C10H1oCl2Nb
Molar mass 294 g/mol
Appearance brown solid
Melting point


Boiling point


Solubility in water soluble (hydrolysis)
Solubility in other solvents sparingly in chlorocarbons
R-phrases 36/37/38
S-phrases 26-36
Related compounds
Related compounds Cp2TiCl2


Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Niobocene dichloride is the organometallic compound with the formula (C5H5)2NbCl2, abbreviated Cp2NbCl2. This paramagnetic brown solid is a starting reagent for the synthesis of other organoniobium compounds. The compound adopts a pseudotetrahedral structure with two cyclopentadienyl and two chloride substituents attached to the metal. A variety of similar compounds are known, including Cp2TiCl2.

It is prepared via a multistep reaction beginning with treatment of niobium pentachloride with cyclopentadienylsodium:[1]

NbCl5 + 6 NaC5H5 → 5 NaCl + (C5H5)4Nb + organic products
(C5H5)4Nb + 2 HCl + 0.5 O2) → [{C5H5)2NbCl}2O]Cl2 + 2 C5H6
2 HCl + [{(C5H5)2NbCl}2O]Cl 2 + SnCl2 → 2 (C5H5)2NbCl2 + SnCl4 + H2O

It was originally reported by Wilkinson.[2] It was investigated as a potential anti-cancer agent.[3]


  1. ^ C. R. Lucas, J. A. Labinger, J. Schwartz (1990). Robert J. Angelici. ed. "Dichlorobis(η5-Cyclopentadienyl)Niobium(IV)". Inorganic Syntheses (New York: J. Wiley & Sons) 28: 267–270. doi:10.1002/9780470132593.ch68. ISBN 0-471-52619-3.  
  2. ^ G. Wilkinson and J.G. Birmingham (1954). "Bis-cyclopentadienyl Compounds of Ti, Zr, V, Nb and Ta". Journal of the American Chemical Society 76 (17): 4281–4284. doi:10.1021/ja01646a008.  
  3. ^ Mokdsi, G.; Harding, M. M. (2001). "A1H NMR study of the Interaction of Antitumor Metallocenes with Glutathione". Journal of Inorganic Biochemistry 86: 611–616. doi:10.1016/S0162-0134(01)00221-5.  


Got something to say? Make a comment.
Your name
Your email address