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IUPAC name
Other names Capstar
CAS number 150824-47-8
ATCvet code QP53BX02
Molecular formula C11H15ClN4O2
Molar mass 270.72 g/mol
Melting point

72 °C[1]

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill insect external parasites of livestock and pets.[2]

In veterinary medicine, it is used orally with dogs and cats to control fleas (often under the brandname "Capstar"[3]). After ingestion, it begins killing fleas within 30 minutes and kills every adult flea on the pet within 4 hours. The effects of this pill are approximately 24-48 hours. Nitenpyram is safe to use on puppies and kittens as young as four weeks old so long as they weigh at least 2 pounds (0.91 kg). However, panting and excitement have been noted in cats within 2 hours of Capstar administration.

Nitenpyram is a neonicotinoid, which means that it is a neurotoxin that blocks the ability for neural messages to transmit through the central nervous system of the flea causing (almost) instant death.

It has no long-term residual activity and therefore is not effective as a longer-term flea preventative. It is usually used to kill adult fleas quickly on an infested animal to give immediate relief for a day. It is then usually followed up with some other longer-term flea preventative to prevent reinfestation. In heavily infested animals, it can cause extreme itching as the fleas die; this almost always resolves on its own.

It is often used as part of the protocol in treating environmental infestations.

External links


  1. ^ Safety (MSDS) data for nitenpyram
  2. ^ Triazophos|Phoxim|Chlorpyrifos|Nitenpyram|Pyridaben|Hexaconazole-Lianyungang Liben Agro-chemical Co.,Ltd
  3. ^ Capstar -


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