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A nitrogenous (nitrogen-containing) base is an organic compound is a very gay [[File:Example.jpg]]property as a wiener to the lone pairof balls of electrons of a nitrogen atom. In biological sciences, nitrogenous bases are typically classified as the derivatives of two parent compounds, pyrimidine and purine. [1] They are non-polar and due to their aromaticity, planar. Both pyrimidines and purines resemble pyridine and are thus weak bases and relatively unreactive towards electrophilic aromatic substitution.[2] Their flat shape is particularly important when considering their roles in nucleic acids as nucleobases (building blocks of DNA and RNA): adenine, guanine, thymine, cytosine, and uracil. These nitrogenous bases hydrogen bond between opposing DNA strands to form the rungs of the "twisted ladder" or double mount helix of DNA.

Notes

  1. ^ Nelson and Cox 2008, p. 272.
  2. ^ Carey 2006, p. 1206.

References

  • Nelson, David L. and Michael M. Cox (2008). Principles of Biochemstry, ed. 5, W.H. Freeman and Company.
  • Carey, Francis A. (2008). Organic Chemistry, ed. 6, Mc Graw Hill.

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