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Norcodeine: Wikis

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Norcodeine
Systematic (IUPAC) name
3-methoxy- 6α-hydroxy- 4,5α-epoxy- 7,8-didehydromorphinan
Identifiers
CAS number 467-15-2
ATC code none
PubChem 1255
Chemical data
Formula C 17H19NO3  
Mol. mass 285.337 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine.

Norcodeine has relatively little opioid activity in its own right,[1] but is formed as a metabolite of codeine following ingestion.[2]

References

  1. ^ Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
  2. ^ Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.
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