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Noribogaine
Systematic (IUPAC) name
12-Hydroxyibogamine
Identifiers
CAS number 481-88-9
ATC code  ?
PubChem 3083548
Chemical data
Formula C 19H24N2O 
Mol. mass 296.407 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status  ? (US) C-I Analogue
Routes Metabolite of Iboga-alkaloid(s?) Ibogaine.

Noribogaine, or 12-hydroxyibogamine, is a major active metabolite of ibogaine, and is thought to be involved in the anti-addictive effects of ibogaine-containing plant extracts.[1][2][3]

See also

References

  1. ^ Glick SD, Maisonneuve IS (May 1998). "Mechanisms of antiaddictive actions of ibogaine". Annals of the New York Academy of Sciences 844: 214–26. PMID 9668680.  
  2. ^ Baumann MH, Pablo J, Ali SF, Rothman RB, Mash DC (2001). "Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine". The Alkaloids. Chemistry and Biology 56: 79–113. PMID 11705118.  
  3. ^ Kubiliene A, Marksiene R, Kazlauskas S, Sadauskiene I, Razukas A, Ivanov L (2008). "Acute toxicity of ibogaine and noribogaine". Medicina (Kaunas, Lithuania) 44 (12): 984–8. PMID 19142057.  
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