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Opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
External IDs OMIM190900 MGI99438 HomoloGene1291 GeneCards: OPN1SW Gene
RNA expression pattern
PBB GE OPN1SW 208036 at tn.png
More reference expression data
Species Human Mouse
Entrez 611 12057
Ensembl ENSG00000128617 ENSMUSG00000058831
UniProt P03999 P51491
RefSeq (mRNA) NM_001708 NM_007538
RefSeq (protein) NP_001699 NP_031564
Location (UCSC) Chr 7:
128.2 - 128.2 Mb
Chr 6:
29.33 - 29.33 Mb
PubMed search [1] [2]

Blue-sensitive opsin is a protein that in humans is encoded by the OPN1SW gene.[1][2][3]

See also


  1. ^ Nathans J, Thomas D, Hogness DS (Apr 1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science 232 (4747): 193-202. PMID 2937147.  
  2. ^ Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). "Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32". Hum Genet 93 (1): 79-80. PMID 8270261.  
  3. ^ "Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)".  

Further reading

  • Applebury ML, Hargrave PA (1987). "Molecular biology of the visual pigments.". Vision Res. 26 (12): 1881–95. doi:10.1016/0042-6989(86)90115-X. PMID 3303660.  
  • Swanson WH, Cohen JM (2003). "Color vision.". Ophthalmology clinics of North America 16 (2): 179–203. doi:10.1016/S0896-1549(03)00004-X. PMID 12809157.  
  • Weitz CJ, Went LN, Nathans J (1992). "Human tritanopia associated with a third amino acid substitution in the blue-sensitive visual pigment.". Am. J. Hum. Genet. 51 (2): 444–6. PMID 1386496.  
  • Weitz CJ, Miyake Y, Shinzato K, et al. (1992). "Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin.". Am. J. Hum. Genet. 50 (3): 498–507. PMID 1531728.  
  • Oprian DD, Asenjo AB, Lee N, Pelletier SL (1992). "Design, chemical synthesis, and expression of genes for the three human color vision pigments.". Biochemistry 30 (48): 11367–72. doi:10.1021/bi00112a002. PMID 1742276.  
  • Sarkar G, Sommer SS (1989). "Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity.". Science 244 (4902): 331–4. doi:10.1126/science.2565599. PMID 2565599.  
  • Nathans J, Piantanida TP, Eddy RL, et al. (1986). "Molecular genetics of inherited variation in human color vision.". Science 232 (4747): 203–10. doi:10.1126/science.3485310. PMID 3485310.  
  • Shimmin LC, Mai P, Li WH (1997). "Sequences and evolution of human and squirrel monkey blue opsin genes.". J. Mol. Evol. 44 (4): 378–82. doi:10.1007/PL00006157. PMID 9089077.  
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.  
  • Gunther KL, Neitz J, Neitz M (2006). "A novel mutation in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect.". Vis. Neurosci. 23 (3-4): 403–9. doi:10.1017/S0952523806233169. PMID 16961973.  


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