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OX40L: Wikis

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tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa)
Identifiers
Symbol TNFSF4
Alt. symbols TXGP1, OX-40L, gp34, CD252
Entrez 7292
HUGO 11934
OMIM 603594
RefSeq NM_003326
UniProt P23510
Other data
Locus Chr. 1 q25

OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.[1] OX40L has also been designated CD252 (cluster of differentiation 252).

References

  1. ^ Maizels RM, Yazdanbakhsh M (2003). "Immune regulation by helminth parasites: cellular and molecular mechanisms". Nat. Rev. Immunol. 3 (9): 733–44. doi:10.1038/nri1183. PMID 12949497. http://www.era.lib.ed.ac.uk/bitstream/1842/465/1/Maizels_%26_Yazdanbakhsh.pdf.  

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