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OXGR1: Wikis


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Oxoglutarate (alpha-ketoglutarate) receptor 1
Symbols OXGR1; GPR80; GPR99; MGC119206; MGC119207; MGC119208; P2RY15; P2Y15
External IDs OMIM606922 MGI2685145 HomoloGene25878 IUPHAR: OXGR1 GeneCards: OXGR1 Gene
RNA expression pattern
File:PBB GE OXGR1 gnf1h10308 at tn.png
More reference expression data
Species Human Mouse
Entrez 27199 239283
Ensembl ENSG00000165621 ENSMUSG00000044819
UniProt Q96P68 Q0VEK6
RefSeq (mRNA) NM_080818 NM_001001490
RefSeq (protein) NP_543008 NP_001001490
Location (UCSC) Chr 13:
96.44 - 96.44 Mb
Chr 14:
119.15 - 119.18 Mb
PubMed search [1] [2]

2-oxoglutarate receptor 1 is a protein that in humans is encoded by the OXGR1 gene.[1][2][3]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][3]


  1. ^ He W, Miao FJ, Lin DC, Schwandner RT, Wang Z, Gao J, Chen JL, Tian H, Ling L (May 2004). "Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors". Nature 429 (6988): 188-93. doi:10.1038/nature02488. PMID 15141213.  
  2. ^ Wittenberger T, Hellebrand S, Munck A, Kreienkamp HJ, Schaller HC, Hampe W (Jul 2003). "GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors". BMC Genomics 3 (1): 17. PMID 12098360.  
  3. ^ a b "Entrez Gene: OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1".  

Further reading

  • Lee DK, Nguyen T, Lynch KR, et al. (2001). "Discovery and mapping of ten novel G protein-coupled receptor genes.". Gene 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.  
  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1-3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Inbe H, Watanabe S, Miyawaki M, et al. (2004). "Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine.". J. Biol. Chem. 279 (19): 19790–9. doi:10.1074/jbc.M400360200. PMID 15001573.  
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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