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Oxatomide: Wikis


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Systematic (IUPAC) name
1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2 H-benzimidazol-2-one
CAS number 60607-34-3
ATC code R06AE06
PubChem 4615
Chemical data
Formula C 27H30N4O 
Mol. mass 426.553 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Oxatomide is a 1st generation antihistamine of the piperazine chemical class.[1] It was discovered at Janssen Pharmaceutica in 1975.

Oxatomide lacks any anticholinergic effects.[1] In addition to its H1 receptor antagonism, it also possesses antiserotonergic actions.[1]


  1. ^ a b c Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N (May 1983). "[Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators]" (in Japanese). Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica 81 (5): 399–409. PMID 6138301.  


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