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Oxotremorine: Wikis

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Oxotremorine
Systematic (IUPAC) name
1-(4-pyrrolidin- 1-ylbut- 2-yn- 1-yl) pyrrolidin- 2-one
Identifiers
CAS number 70-22-4
ATC code none
Chemical data
Formula C12H18N2O 
Mol. mass 206.28
Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Oxotremorine is a cholinomimetic that acts as a non-selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

References

  1. ^ Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013. 
  2. ^ Craig, C. R., Stitzel, R. E., Modern Pharmacology. Little, Brown. Boston, 2006.
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