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Oxypertine
Systematic (IUPAC) name
5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole
Identifiers
CAS number 153-87-7
ATC code N05AE01
PubChem 4640
Chemical data
Formula C23H29N3O2 
Mol. mass 379.49 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.[1] Chemically, it is an indole derivative similarly to molindone.[2] Like reserpine and tetrabenazine, oxypertine depletes catecholamines, though not serotonin, possibly underlying its neuroleptic efficacy.[3]

See also

References

  1. ^ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8. http://books.google.com/books?id=5S_uhYzKWisC&lpg=PA5038&dq=oxypertine%20forit&as_brr=3&pg=PA5038#v=onepage&q=&f=false. 
  2. ^ Breulet M, Labar P, Delree C, Collard J, Bobon J (February 1968). "[Oxypertine, peperazine derivative of tryptophan with neuroleptic and dynamogenic properties]" (in French). Acta Neurol Psychiatr Belg 68 (2): 116–27. PMID 4972600. 
  3. ^ Bak IJ, Hassler R, Kim JS (1969). "Differential monoamine depletion by oxypertine in nerve terminals. Granulated synaptic vesicles in relation to depletion of norepinephrine, dopamine and serotonin". Zeitschrift Für Zellforschung Und Mikroskopische Anatomie (Vienna, Austria : 1948) 101 (3): 448–62. PMID 5362847. 
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