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Purinergic receptor P2Y, G-protein coupled, 13
Symbols P2RY13; GPCR1; FKSG77; GPR86; GPR94; P2Y13; SP174
External IDs OMIM606380 MGI1921441 HomoloGene12543 IUPHAR: P2Y13 GeneCards: P2RY13 Gene
RNA expression pattern
PBB GE P2RY13 220005 at tn.png
More reference expression data
Species Human Mouse
Entrez 53829 74191
Ensembl ENSG00000181631 ENSMUSG00000036362
UniProt Q9BPV8 Q0VF10
RefSeq (mRNA) NM_023914 NM_028808
RefSeq (protein) NP_076403 NP_083084
Location (UCSC) Chr 3:
152.53 - 152.53 Mb
Chr 3:
59.3 - 59.3 Mb
PubMed search [1] [2]

P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.[1][2][3]

The product of this gene, P2Y13, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. Two transcript variants encoding the same protein have been identified for this gene.[3]


See also


  1. ^ Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol 307 (3): 799-813. doi:10.1006/jmbi.2001.4520. PMID 11273702.  
  2. ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83-91. PMID 11574155.  
  3. ^ a b "Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13".  

External links

Further reading

  • Communi D, Gonzalez NS, Detheux M, et al. (2001). "Identification of a novel human ADP receptor coupled to G(i).". J. Biol. Chem. 276 (44): 41479–85. doi:10.1074/jbc.M105912200. PMID 11546776.  
  • Zhang FL, Luo L, Gustafson E, et al. (2002). "P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse.". J. Pharmacol. Exp. Ther. 301 (2): 705–13. doi:10.1124/jpet.301.2.705. PMID 11961076.  
  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1-3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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