The Full Wiki

More info on PNRC1

PNRC1: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Proline-rich nuclear receptor coactivator 1
Symbols PNRC1; PRR2; B4-2; PNAS-145; PROL2; RP11-63L7.5
External IDs OMIM606714 MGI1917838 HomoloGene4960 GeneCards: PNRC1 Gene
RNA expression pattern
PBB GE PNRC1 209034 at tn.png
More reference expression data
Species Human Mouse
Entrez 10957 108767
Ensembl ENSG00000146278 ENSMUSG00000040128
UniProt Q12796 n/a
RefSeq (mRNA) NM_006813 XM_980235
RefSeq (protein) NP_006804 XP_985329
Location (UCSC) Chr 6:
89.85 - 89.85 Mb
Chr 4:
33.57 - 33.58 Mb
PubMed search [1] [2]

Proline-rich nuclear receptor coactivator 1 is a protein that in humans is encoded by the PNRC1 gene.[1][2]


  1. ^ Chen J, Liu L, Pohajdak B (Dec 1995). "Cloning a cDNA from human NK/T cells which codes for a protein with high proline content". Biochim Biophys Acta 1264 (1): 19-22. PMID 7578250.  
  2. ^ "Entrez Gene: PNRC1 proline-rich nuclear receptor coactivator 1".  

External links

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Zhou D, Chen B, Ye JJ, Chen S (2004). "A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction.". Oncogene 23 (31): 5394–404. doi:10.1038/sj.onc.1207695. PMID 15122321.  
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Zhou D, Chen S (2001). "PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif.". Nucleic Acids Res. 29 (19): 3939–48. PMID 11574675.  
  • Zhou D, Quach KM, Yang C, et al. (2000). "PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1).". Mol. Endocrinol. 14 (7): 986–98. doi:10.1210/me.14.7.986. PMID 10894149.  
  • Hsiao PW, Chang C (1999). "Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells.". J. Biol. Chem. 274 (32): 22373–9. doi:10.1074/jbc.274.32.22373. PMID 10428808.  


Got something to say? Make a comment.
Your name
Your email address