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Proline-rich nuclear receptor coactivator 1
Identifiers
Symbols PNRC1; PRR2; B4-2; PNAS-145; PROL2; RP11-63L7.5
External IDs OMIM606714 MGI1917838 HomoloGene4960 GeneCards: PNRC1 Gene
RNA expression pattern
PBB GE PNRC1 209034 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10957 108767
Ensembl ENSG00000146278 ENSMUSG00000040128
UniProt Q12796 n/a
RefSeq (mRNA) NM_006813 XM_980235
RefSeq (protein) NP_006804 XP_985329
Location (UCSC) Chr 6:
89.85 - 89.85 Mb
Chr 4:
33.57 - 33.58 Mb
PubMed search [1] [2]

Proline-rich nuclear receptor coactivator 1 is a protein that in humans is encoded by the PNRC1 gene.[1][2]

References

  1. ^ Chen J, Liu L, Pohajdak B (Dec 1995). "Cloning a cDNA from human NK/T cells which codes for a protein with high proline content". Biochim Biophys Acta 1264 (1): 19-22. PMID 7578250.  
  2. ^ "Entrez Gene: PNRC1 proline-rich nuclear receptor coactivator 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10957.  

External links

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Zhou D, Chen B, Ye JJ, Chen S (2004). "A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction.". Oncogene 23 (31): 5394–404. doi:10.1038/sj.onc.1207695. PMID 15122321.  
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Zhou D, Chen S (2001). "PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif.". Nucleic Acids Res. 29 (19): 3939–48. PMID 11574675.  
  • Zhou D, Quach KM, Yang C, et al. (2000). "PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1).". Mol. Endocrinol. 14 (7): 986–98. doi:10.1210/me.14.7.986. PMID 10894149.  
  • Hsiao PW, Chang C (1999). "Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells.". J. Biol. Chem. 274 (32): 22373–9. doi:10.1074/jbc.274.32.22373. PMID 10428808.  
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