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Pagibaximab: Wikis

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From Wikipedia, the free encyclopedia

Pagibaximab ?
Monoclonal antibody
Source Chimeric
Target Staphylococcal lipoteichoic acid
Identifiers
CAS number 595566-61-3
ATC code none
PubChem  ?
Chemical data
Formula C 6462H9996N1728O2028S54  
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Pagibaximab is a chimeric monoclonal antibody for the prevention of staphylococcal sepsis in infants with low birth weight. As of July 2009, it is undergoing Phase I/II clinical trials.[1]

References

  1. ^ Weisman, LE; Thackray; Garcia-Prats; Nesin; Schneider; Fretz; Kokai-Kun; Mond et al. (2009). "Phase 1/2 double-blind, placebo-controlled, dose escalation, safety, and pharmacokinetic study of pagibaximab (BSYX-A110), an antistaphylococcal monoclonal antibody for the prevention of staphylococcal bloodstream infections, in very-low-birth-weight neonates". Antimicrobial agents and chemotherapy 53 (7): 2879–86. doi:10.1128/AAC.01565-08. PMID 19380597.  

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