The Full Wiki

More info on Pangamic acid

Pangamic acid: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Pangamic acid
Pangamic acid.png
IUPAC name
Other names Vitamin B15; Gluconodimethylaminoacetic acid
Identifiers
CAS number 20858-86-0
SMILES
Properties
Molecular formula C10H19NO8
Molar mass 281.26 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pangamic acid is an ester derived from gluconic acid and dimethylglycine.[1] It was first isolated by Ernst T. Krebs from apricot kernels,[2] and has since been identified in some foods such as pulses[3] and rice bran.

Pangamic acid was also promoted by Krebs as vitamin B15, but it is not accepted as a vitamin because it has not been shown to be essential in the human diet, and a deficiency in consumption of pangamic acid is not known to be associated with any disease.[4]

The calcium salt of pangamic acid, calcium pangamate, is used as a mineral supplement. Like thiamine, pangamic acid causes a temporary drop in blood pressure lasting for about 20 minutes.

References

  1. ^ Recent data on the structure of pangamic acid (vitamin B15). Telegdy Kovats, Laszlo; Berndorfer-Kraszner, Eva; Juhasz, Agnes; Gabor, Tamas. Acta Alimentaria Academiae Scientiarum Hungaricae (1976), 5(3), 281-8.
  2. ^ KREBS E T Sr; KREBS E T Jr; BEARD H H; MALIN R; HARRIS A T; BARTLETT C L Pangamic acid sodium: a newly isolated crystalline water-soluble factor; a preliminary report. International record of medicine and general practice clinics (1951), 164(1), 18-23.
  3. ^ Singh, Jagdev; Handa, Mrs. Geeta; Nandi, L. N.; Manavalan, R.; Atal, C. K. D-Gluconodimethylaminoacetic acid from natural sources. Indian Drugs (1983), 20(5), 185-9.
  4. ^ "Vitamin B15 - Pangamic Acid", Elson M. Haas M.D.
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message