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Para-Methoxyethylamphetamine: Wikis

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Systematic (IUPAC) name
CAS number 14367-46-5 93963-24-7 (hydrochloride)
ATC code  ?
PubChem 85725
Chemical data
Formula C 12H19NO 
Mol. mass 193.285 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Paramethoxyethylamphetamine (PMEA), is a stimulant drug related to PMA. PMEA reputedly produces similar effects to PMA, but is considerably less potent [1] and seems to have slightly less tendency to produce severe hyperthermia, at least at low doses. At higher doses however the side effects and danger of death approach those of PMA itself, and PMEA should still be considered a potentially dangerous drug. Investigation of a drug-related death in Japan in 2005 showed PMEA to be present in the body and was thought to be responsible for the death.[2]


  1. ^ Bustamante D, Diaz-Veliz G, Paeile C, Zapata-Torres G, Cassels BK. Analgesic and behavioral effects of amphetamine enantiomers, p-methoxyamphetamine and n-alkyl-p-methoxyamphetamine derivatives. Pharmacology, Biochemistry and Behavior. 2004 Oct;79(2):199-212.
  2. ^ Zaitsu K, Katagi M, Kamata T, Kamata H, Shima N, Tsuchihashi H, Hayashi T, Kuroki H, Matoba R. Determination of a newly encountered designer drug "p-methoxyethylamphetamine" and its metabolites in human urine and blood. Forensic Science International. 2008 May 2;177(1):77-84. PMID 18155375

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