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Pegaspargase
Systematic (IUPAC) name
Pegylated E. coli L-asparagine amidohydrolase
Identifiers
CAS number 130167-69-0
ATC code L01XX24
PubChem  ?
DrugBank BTD00079
Chemical data
Formula C 1377H2208N382O442S17  
Mol. mass 31731.9 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Pegaspargase is an antineoplastic agent.

It is used in the treatment of acute lymphoblastic leukemia.[1]

It is a form of L-asparaginase[2] which has undergone PEGylation.

References

  1. ^ Graham ML (2003). "Pegaspargase: a review of clinical studies". Adv. Drug Deliv. Rev. 55 (10): 1293–302. doi:10.1016/S0169-409X(03)00110-8. PMID 14499708.  
  2. ^ "UNM Cancer Center". http://cancer.unm.edu/drug_dictionary.aspx?id=818. Retrieved 2007-08-28.  







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